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Summit Research is a medical research organization located in the greater Portland, Oregon area. Since 1976, we remain dedicated to improving medical treatment by conducting high quality scientific research and patient care.
Alzheimer’s Clinical Trials in Portland, Oregon
Leading Alzheimer’s Research Studies In Oregon
As we grow older, changes in the brain can give rise to concerns about memory. While certain cognitive changes are a normal part of aging, others could potentially indicate the onset of Alzheimer's disease.
Alzheimer's disease is a degenerative disorder that progressively destroys nerve cells, or neurons, in the brain. This deterioration leads to memory loss, as well as difficulties with thinking and behavior. Over time, the symptoms of the disease worsen.
- It is the sixth-leading cause of death in the United States.
- It is estimated that 5.8 million Americans have Alzheimer’s disease.
- Every 65 seconds someone is diagnosed with Alzheimer’s disease.
- The number of people with Alzheimer’s disease is expected to increase by 88 million by 2050.
- Significant memory loss is not a normal part of growing older or aging. It is often one of the first signs of Alzheimer’s disease.
While other leading causes of death are decreasing, the prevalence of Alzheimer's disease is steadily increasing. Although there is presently no known cure for Alzheimer's, early evaluation and treatment can potentially extend memory function and enhance long-term quality of life. The invaluable insights gained through clinical trials offer hope for the development of more effective treatments and ultimately, a potential cure.
Common Symptoms Associated With Early Stages Of Alzheimer’s Disease
Memory problems are frequently among the initial indications of Alzheimer's disease. The symptoms can differ from one person to another and may encompass various challenges related to:
- Difficulty with word-finding, experiencing more challenges in generating words compared to peers of the same age.
- Issues with vision and spatial awareness, such as reduced perception of the surrounding space.
- Impaired reasoning and judgment, potentially affecting decision-making processes.
Other symptoms may be changes in the person’s behavior, including:
- Experiencing delays in completing everyday tasks.
- Asking the same questions repeatedly.
- Struggling with managing finances and paying bills.
- Getting lost or wandering.
- Misplacing items in unusual locations.
- Noticing changes in mood and personality.
- Feeling increased anxiety and/or displaying aggression.
Understanding Alzheimer's Disease: What We Know
The precise causes of Alzheimer's disease have not yet been fully comprehended by scientists. It's believed that there isn't a solitary cause, but rather a combination of various factors that can impact individuals in different ways.
- Age represents the most well-known risk factor for Alzheimer's disease.
- Family history suggests that genetics may contribute to the development of Alzheimer's disease. However, it's important to note that genes alone do not determine destiny. Embracing a healthy lifestyle can potentially reduce the risk of developing Alzheimer's disease. Two extensive, long-term studies have indicated that engaging in sufficient physical activity, maintaining a nutritious diet, limiting alcohol consumption, and abstaining from smoking can be beneficial. To delve deeper into the study, you can listen to a concise podcast.
- The changes in the brain can commence years before the initial symptoms manifest.
- Researchers are currently examining the potential impact of education, diet, and environment on the development of Alzheimer's disease.
- An increasing body of scientific evidence suggests that adopting healthy behaviors, which have been proven to prevent cancer, diabetes, and heart disease, may also lower the risk of subjective cognitive decline. Here are eight effective strategies to maintain a healthy body and brain.
Alzheimer's And The Brain
The early stages of memory loss are preceded by subtle changes in the brain at a microscopic level. With approximately 100 billion nerve cells, the brain forms intricate communication networks as each cell connects with numerous others. These cells have specific functions, some dedicated to cognition, learning, and memory, while others contribute to our sensory perceptions.
Within the brain, these cells operate like miniature factories, receiving supplies, producing energy, assembling equipment, and disposing of waste. They also process and store information and establish communication with neighboring cells. This intricate operation demands coordination, as well as a significant amount of fuel and oxygen.
Scientists hypothesize that Alzheimer's disease disrupts the proper functioning of cellular factories, although the exact point of origin remains unknown. Similar to a physical factory, malfunctions and backups in one system can have cascading effects on other areas. As the damage spreads, cells gradually lose their capacity to perform their designated tasks and eventually perish, leading to irreversible changes within the brain.
The Role Of Plaques And Tangles
Plaques and tangles, two abnormal structures, are believed to be the main culprits behind the damage and destruction of nerve cells. These structures are implicated in causing harm and ultimately leading to their demise.
- Plaques consist of a protein fragment known as beta-amyloid that accumulates in the gaps between nerve cells.
- Tangles are intricate fibers of another protein named "tau" that amass within cells.
Autopsy studies reveal that as individuals age, it is common to develop plaques and tangles in the brain. However, those with Alzheimer's disease experience a more pronounced and predictable pattern of plaque and tangle formation, initially affecting the regions crucial for memory before spreading to other areas.
The exact role of plaques and tangles in Alzheimer's disease remains uncertain. Nonetheless, most experts believe that they play a significant role in disrupting communication between nerve cells and interfering with vital cellular processes necessary for survival.
It is the destruction and loss of nerve cells that ultimately leads to memory impairment, personality changes, difficulties in daily activities, and other symptoms associated with Alzheimer's disease.
How To Participate In Our Alzheimer's Clinical Research Trials In Portland
Summit Research offers residents of Oregon the chance to take part in clinical research trials covering a range of therapeutic areas. With new studies being added every week, you now have the opportunity to make a real impact by joining an Alzheimer's clinical trial at Summit Research and contributing to the ongoing fight against Alzheimer's. By participating, not only will you help advance the field of medicine, but you will also enjoy a host of benefits that come with being a part of this important endeavor.
- Learn about potential new medicines in development
- Get study-related medical exams at no cost
- You may receive investigational medications that are not available to the general population
- Study-related medical care; depending on the study this may include psychological evaluation, cognitive assessments, medical evaluations, physical exams, lab work, and diagnostic imaging (such as CT scans, MRI, or PET scans). With your permission, the results of these evaluations and assessments may be provided to your primary healthcare provider
- Ongoing study check-ups throughout the study
- Education and up-to-date information about your condition
- Depending on the trial, a stipend or compensation for time and travel may be available
Enroll In A Portland Alzheimer's Clinical Trial Today
To find out about the Alzheimer's research studies currently enrolling patients in your Portland community and determine your eligibility, we suggest completing the form on this page or reaching out to us directly to speak with an enrollment specialist.
Once you've provided your information, a Summit Research enrollment specialist will contact you. Together, we'll explore the studies that may be suitable for you and address any questions you may have. It's important to note that health insurance is not required to participate, and there is absolutely no obligation to join. Our aim is to help you make an informed decision.
Contact Summit Research
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